VASCo is a program pipeline including a visualization tool to calculate and visualize annotated surfaces with special emphasis on surface contact regions and protein-protein interactions. Crystal contacts and biological contacts can be calculated based on surface points. Molecular properties such as electrostatic potential or hydrophobicity can be calculated and mapped on those surface points. The molecular surfaces and properties are calculated using existing established programs, which are integrated into the package, as well as using own developed programs. The modular pipeline can easily be extended to include new properties for annotation. The output of this pipeline is most conveniently displayed in PyMOL as Compiled Graphics Objects (CGO) using a custom-made plug-in.
The software is available only to academic, government, and other nonprofit institutions for noncommercial, nonprofit internal research purposes. Details about license can be found at official site.
module add vasco-1.0.2 VASCo.py -h
Notice: This application use or needs GUI – graphical interface. To use the application in graphical mode see Remote desktop or X-Window.
VASCo can be added as plugin to PyMOL application - script used for this kind of set up can be found at /software/vasco/1.0.2/ppixplugin_v077.py.