SOLpro

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Description

SOLpro predicts the propensity of a protein to be soluble upon overexpression in E. coli using a two-stage SVM architecture based on multiple representations of the primary sequence. Each classifier of the first layer takes as input a distinct set of features describing the sequence. A final SVM classifier summarizes the resulting predictions and predicts if the protein is soluble or not as well as the corresponding probability.

Availability

Only one unnumbered version from 2009.

solpro

Use

module add solpro
predict_sol.sh input output

Documentation

http://scratch.proteomics.ics.uci.edu/explanation.html#SOLpro
http://download.igb.uci.edu/

Licence

Download SOLpro (free for academic, non commercial, use)

Program manager

meta@cesnet.cz

Homepage

http://scratch.proteomics.ics.uci.edu/explanation.html#SOLpro