Omni-c

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Description

Omni-C Libraries Enable Genome Wide Resolution of Chromatin Interactions. By employing a sequence-independent endonuclease for chromatin digestion, Omni-C™ offers all the characteristics of Hi-C libraries, without the sequence bias inherent to restriction enzyme (RE) based Hi-C approaches. Omni-C™ data contains a significant overlap with data generated using RE based approaches, but are enriched in long-range cis reads. Improved resolution for chromatin conformation and looping interactions can be measured due to this lack of sequence bias. Omni-C™ libraries enable the most complete view of genome-wide chromatin conformation by dramatically increasing resolution of topological interactions that occur in regions with low restriction enzyme density.

Availability

version 0.1


Use

module add omnic-0.1

get_qc.py -h


Documentation

https://omni-c.readthedocs.io/en/latest/index.html


Licence

Public

Program manager

meta@cesnet.cz

Homepage

https://omni-c.readthedocs.io/en/latest/index.html