Kraken2

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Description

Kraken 2 is the newest version of Kraken, a taxonomic classification system using exact k-mer matches to achieve high accuracy and fast classification speeds. This classifier matches each k-mer within a query sequence to the lowest common ancestor (LCA) of all genomes containing the given k-mer. The k-mer assignments inform the classification algorithm.

Licence

Public

Usage

Upcoming modulesystem change alert!

Due to large number of applications and their versions it is not practical to keep them explicitly listed at our wiki pages. Therefore an upgrade of modulefiles is underway. A feature of this upgrade will be the existence of default module for every application. This default choice does not need version number and it will load some (usually latest) version.

You can test the new version now by adding a line

source /cvmfs/software.metacentrum.cz/modulefiles/5.1.0/loadmodules

to your script before loading a module. Then, you can list all versions of kraken2 and load default version of kraken2 as

module avail kraken2/ # list available modules
module load kraken2   # load (default) module


If you wish to keep up to the current system, it is still possible. Simply list all modules by

module avail kraken2

and choose explicit version you want to use.

There is NT Kraken2 database available in shared location, in order to use it, run

       kraken2 --db /storage/brno12-cerit/projects/Bio_databases/kraken2_nt_20230502

and request at least mem=500gb (unless only short query is processed with --memory-mapping option). For optimal performance of access to this database, we recommend adding another qsub requirement pbs_server=cerit-pbs.cerit-sc.cz or cluster=halmir (these select (two different sets of) machines with fastest network connection to the database storage).

Documentation

https://ccb.jhu.edu/software/kraken2/index.shtml?t=manual

Homepage

https://ccb.jhu.edu/software/kraken2/index.shtml