Bcl2fastq2

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Description

The Illumina sequencing instruments generate per-cycle base call (BCL) files at the end of the sequencing run. A majority of analysis applications use per-read FASTQ files as input for analysis. You can use the bcl2fastq2 Conversion Software to convert basecall (BCL) files from a sequencing run into FASTQ files.

The bcl2fastq2 Conversion Software supports the following instruments:

  • MiniSeq
  • MiSeq
  • NextSeq 500, 550
  • HiSeq X
  • HiSeq 2000, 2500, 3000, 4000

License

This Software is licensed for use under an End User Software License Agreement

Usage

Upcoming modulesystem change alert!

Due to large number of applications and their versions it is not practical to keep them explicitly listed at our wiki pages. Therefore an upgrade of modulefiles is underway. A feature of this upgrade will be the existence of default module for every application. This default choice does not need version number and it will load some (usually latest) version.

You can test the new version now by adding a line

source /cvmfs/software.metacentrum.cz/modulefiles/5.1.0/loadmodules

to your script before loading a module. Then, you can list all versions of obcl2fastq2 and load default version of obcl2fastq2 as

module avail obcl2fastq2/ # list available modules
module load obcl2fastq2   # load (default) module


If you wish to keep up to the current system, it is still possible. Simply list all modules by

module avail obcl2fastq2

and choose explicit version you want to use.

Documentation

http://jp.support.illumina.com/content/dam/illumina-support/documents/downloads/software/bcl2fastq/bcl2fastq2-v2-18-software-guide-15051736-01.pdf

Homepage

https://support.illumina.com/sequencing/sequencing_software/bcl2fastq-conversion-software.html